Colt E W, Dunner D L, Wang J, Ross D C, Pierson R N, Fieve R R
Arch Gen Psychiatry. 1982 May;39(5):577-81. doi: 10.1001/archpsyc.1982.04290050051010.
The body composition of three unipolar and 17 bipolar patients, studied during the depressive state, was compared with that of 48 controls. The ratio of extracellular to intracellular water content was significantly less in male patients than in male controls: the difference between female patients and female controls was not statistically significant. In patients of both sexes, residual sodium concentration was greater in patients than in controls. The intracellular content of potassium was the same in patients as in controls. In six patients, body composition was studied prior to lithium carbonate therapy, after 17 days of treatment, and 17 days after discontinuing administration of the drug. The significant changes were a decrease in body weight during therapy, and a decrease in body water content and an increase in residual sodium concentration after drug treatment was discontinued.
对3名单相抑郁症患者和17名双相抑郁症患者在抑郁状态下的身体成分进行了研究，并与48名对照组进行了比较。男性患者细胞外与细胞内水含量的比率显著低于男性对照组：女性患者与女性对照组之间的差异无统计学意义。在男女患者中，患者的残余钠浓度均高于对照组。患者的细胞内钾含量与对照组相同。对6名患者在碳酸锂治疗前、治疗17天后以及停药17天后的身体成分进行了研究。显著变化包括治疗期间体重下降，停药后身体水分含量下降以及残余钠浓度增加。
