Fischbacher E
Br Med J (Clin Res Ed). 1982 Aug 7;285(6339):423-4. doi: 10.1136/bmj.285.6339.423.
An attempt was made over a period of a year to reduce the number of anticonvulsants used to treat epilepsy in a hospital for the mentally handicapped. At least one drug was withdrawn for each of 20 patients, without loss of seizure control. Effect on wellbeing was assessed by a behavioural scale completed before and after withdrawal, and in the 20 cases of successful withdrawal wellbeing was significantly improved.
在一年的时间里,一家智障人士医院尝试减少用于治疗癫痫的抗惊厥药物数量。对20名患者中的每一位至少停用了一种药物,且癫痫控制未受影响。通过停药前后完成的行为量表评估对健康状况的影响,在20例成功停药的病例中,健康状况得到显著改善。