Heslop J H
Burns Incl Therm Inj. 1982 Jul;8(6):436-8. doi: 10.1016/0305-4179(82)90116-4.
The pathogenesis of this rather rare complication of burn injury is discussed. Injury and bleeding as a result of enthusiastic physiotherapy are usually incriminated as the major cause of such bone formation. More recent work is quoted which suggests that increased nutritional support regimes, particularly in respect of protein, cause a calciuretic response in burn patients. This iatrogenic mobilization of calcium, together with the increased levels of calcium due to injury and bed rest, may precipitate this complication. The periarticular location usually seen in burns, as compared with the heterotopic sites in muscle following other forms of injury, is noted. Although spontaneous resolution can sometimes occur, an active approach, with surgical excision being early rather than deferred, is advocated.
本文讨论了烧伤这种较为罕见并发症的发病机制。积极的物理治疗导致的损伤和出血通常被认为是这种骨形成的主要原因。文中引用了近期的研究，该研究表明营养支持方案的增加，尤其是蛋白质方面，会使烧伤患者产生利钙反应。这种医源性钙动员，加上损伤和卧床休息导致的钙水平升高，可能会引发这种并发症。文中指出，与其他形式损伤后肌肉中的异位部位相比，烧伤中常见的关节周围部位。尽管有时会自发消退，但仍提倡采取积极的治疗方法，早期而非延迟进行手术切除。
