Colding H, Møller S, Andersen G E
Arch Dis Child. 1982 Aug;57(8):602-6. doi: 10.1136/adc.57.8.602.
Ampicillin and gentamicin were dissolved once a day in an L-amino acid solution especially prepared for parenteral nutrition of newborn infants and infused continuously to 88 infants in whom septicaemia was suspected or had been proved. The mean dosages were 162 and 5.3 mg/kg per 24 hours respectively, and the 95% limits for the serum concentrations were 11-133 and 1.3-7.4 micrograms/ml. The treatment results were at least as good as with intermittent intramuscular or intravenous administration. This new mode of giving antibiotics is less painful to the babies and easier for the nurses.
氨苄青霉素和庆大霉素每天一次溶解于专门为新生儿肠外营养配制的L-氨基酸溶液中，并持续输注给88名疑似或已被证实患有败血症的婴儿。平均剂量分别为每24小时162毫克/千克和5.3毫克/千克，血清浓度的95%限值分别为11 - 133微克/毫升和1.3 - 7.4微克/毫升。治疗效果至少与间歇性肌肉注射或静脉注射一样好。这种新的抗生素给药方式对婴儿的痛苦较小，对护士来说也更容易操作。
