肠外营养期间氧消耗和二氧化碳产生的变化。

Variations in oxygen consumption and carbon dioxide production during parenteral nutrition.

作者信息

Fernandez Mondejar E, Duro Lombardo M, Perez de la Cruz A J, Merida Morales A, Torres Ruiz J M, Ferron Orihuela J A

出版信息

Intensive Care Med. 1982;8(4):169-72. doi: 10.1007/BF01725733.

Abstract

To verify that variations caused by total parenteral nutrition (TPN) in O2 intake (VO2) and CO2 output (VCO2) can affect respiratory function of non-hypercatabolic patients, we studied 18 patients in two groups; group I (control): eight patients receiving 75-100 g glucose/24 h, and group II: ten patients fed intravenously on 13.6 g N2 and approximately 2,800 kcal/24 h given as a) 62% glucose + 38% fats (TPN-G + F) and b) 100% glucose (TPN-G). VO2, VCO2, respiratory quotient (RQ) and minute ventilation (VE) were measured in all patients. We found that VCO2 was 27% higher in intravenously fed patients (p less than 0.01 and p less than 0.02). Similarly, VE was 26% higher in intravenously fed patients (p less than 0.001 and p less than 0.02). Comparison of TPN-G + F and TPN-G results showed no differences in VCO2; by contrast, VO2 was 21% less during TPN-G (p less than 0.01).

摘要

为了验证全胃肠外营养（TPN）引起的氧气摄入量（VO2）和二氧化碳排出量（VCO2）的变化是否会影响非高分解代谢患者的呼吸功能，我们将18例患者分为两组进行研究；第一组（对照组）：8例患者每天接受75 - 100克葡萄糖；第二组：10例患者静脉输注13.6克氮以及约2800千卡/天，分别以以下方式给予：a）62%葡萄糖 + 38%脂肪（TPN-G + F）和b）100%葡萄糖（TPN-G）。测量了所有患者的VO2、VCO2、呼吸商（RQ）和分钟通气量（VE）。我们发现静脉喂养患者的VCO2高27%（p < 0.01和p < 0.02）。同样，静脉喂养患者的VE高26%（p < 0.001和p < 0.02）。TPN-G + F和TPN-G结果的比较显示VCO2无差异；相比之下，TPN-G期间VO2少21%（p < 0.01）。