Radwanska E, Headley S K, Dmowski P
J Reprod Med. 1982 Jul;27(7):376-84.
Many women appear to experience menstrual disturbances after tubal sterilization. In this study the ovarian function in such women was investigated. Serial measurements of FSH, LH, estradiol and progesterone were performed throughout the study cycle in 23 previously sterilized patients, 14 with menstrual disturbances (group I--symptomatic) and 9 with normal cycles (group II--asymptomatic). A group of 28 parous women served as controls. Among 23 patients, luteal phase progesterone was elevated in 19, and in 4 it was undetectable (anovulatory). All four anovulatory patients belonged to group I. Anovulatory cycles were also characterized by tonic elevated LH levels. Mean midluteal progesterone values were lower in group I (8.5 ng/ml) than in group II (13.8 ng/ml) and in the controls (16.5 ng/ml). Mean midluteal progesterone was lower than 10 ng/ml in 78% of group I, 44% of group II and 15% of the control patients.
许多女性在输卵管绝育术后似乎会出现月经紊乱。在本研究中,对这类女性的卵巢功能进行了调查。在整个研究周期中,对23例先前接受绝育手术的患者进行了促卵泡生成素(FSH)、促黄体生成素(LH)、雌二醇和孕酮的系列测量,其中14例有月经紊乱(I组——有症状),9例月经周期正常(II组——无症状)。一组28例经产妇作为对照。在23例患者中,19例黄体期孕酮升高,4例未检测到(无排卵)。所有4例无排卵患者均属于I组。无排卵周期的特征还包括LH水平持续升高。I组的平均黄体中期孕酮值(8.5 ng/ml)低于II组(13.8 ng/ml)和对照组(16.5 ng/ml)。I组78%、II组44%和对照组15%的患者黄体中期孕酮平均低于10 ng/ml。