Gamble W C, Chappell W A, George E H
Health Lab Sci. 1978 Apr;15(2):91-4.
Mouse immune ascitic fluid has become a primary source of antibody for diagnostic, reference, and research work in many virus laboratories. The inherent disadvantage of ascitic fluid is that it repeatedly forms clots and subsequently loses volume. The acid-precipitation method of Chiewsilp and McCown eliminates the clot formation and does not appreciably alter the antibody titers for several arboviruses, varicella, rabies and influenza viruses.
小鼠免疫腹水已成为许多病毒实验室用于诊断、参考和研究工作的主要抗体来源。腹水的固有缺点是它会反复形成凝块并随后减少体积。Chiewsilp和McCown的酸沉淀法消除了凝块形成，并且不会明显改变几种虫媒病毒、水痘、狂犬病和流感病毒的抗体效价。
