辅助疫苗对2型登革病毒免疫腹水产生的影响。
Effect of adjuvant vaccines on dengue virus type 2 immune ascitic fluid production.
作者信息
Gamble W C, George E H, Fears M B, Sanderlin D W, Chappell W A
出版信息
J Clin Microbiol. 1985 Mar;21(3):452-3. doi: 10.1128/jcm.21.3.452-453.1985.
Abstract
In a comparison of dengue type 2 immune mouse ascitic fluid immunization schedules, a schedule in which adjuvant vaccines were not used produced neutralizing antibody titers that were specific and a mouse mortality rate that was lower, resulting in a greater yield of ascitic fluids. In the schedules in which emulsified adjuvant vaccines were used, the quality of the emulsion had little effect on antibody titer produced.
摘要
在对登革热2型免疫小鼠腹水免疫方案的比较中，未使用佐剂疫苗的方案产生了特异性的中和抗体滴度，且小鼠死亡率较低，从而产生了更高产量的腹水。在使用乳化佐剂疫苗的方案中，乳液质量对产生的抗体滴度影响不大。
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