Sharma J M, Coulson B D
J Natl Cancer Inst. 1977 Jun;58(6):1647-51. doi: 10.1093/jnci/58.6.1647.
In a microcytotoxicity test in which 51Cr-labeled cells of a Marek's disease (MD) lymphoblastoid line (MSB-1 line) were used, cell-mediated cytotoxicity of spleen cell suspensions prepared from chickens inoculated with MD virus was demonstrated. This cytotoxic response, presumably directed against MD tumor-associated surface antigen, was detectable briefly after virus infection and paralleled the appearance of early lymphoproliferative lesions characteristic of MD.
在一项微量细胞毒性试验中，使用了经51Cr标记的马立克氏病（MD）淋巴母细胞系（MSB - 1系）细胞，结果表明，接种MD病毒的鸡所制备的脾细胞悬液具有细胞介导的细胞毒性。这种细胞毒性反应可能是针对MD肿瘤相关表面抗原的，在病毒感染后短时间内即可检测到，并且与MD早期特征性淋巴增生性病变的出现平行。
