• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

Location of ribosome-binding sites on the tetracycline resistance transposon Tn10.

作者信息

Calame K, Nakada D, Ihler G

出版信息

J Bacteriol. 1978 Aug;135(2):668-74. doi: 10.1128/jb.135.2.668-674.1978.

DOI:10.1128/jb.135.2.668-674.1978
PMID:681286
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC222428/
Abstract

Eight ribosome-binding sites were located on the single-stranded Tn10 DNA loop which was formed after denaturation of lambda phage DNA containing the Tn10 transposon sequence. Ribosomes were bound only to the Tn10 loop contained on the R strand of lambda DNA but not to that on the L strand, suggesting that one of the two strands of Tn10 DNA is selectively transcribed. Six of the eight ribosome binding sites were located in one-half of the DNA loop. The maximum sizes of potential polypeptides were calculated for these genes to range between 9,500 and 84,000 daltons.

摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4418/222428/9a452936fe4f/jbacter00291-0386-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4418/222428/5f5bd33ac8c3/jbacter00291-0384-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4418/222428/9a452936fe4f/jbacter00291-0386-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4418/222428/5f5bd33ac8c3/jbacter00291-0384-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4418/222428/9a452936fe4f/jbacter00291-0386-a.jpg

相似文献

1
Location of ribosome-binding sites on the tetracycline resistance transposon Tn10.
J Bacteriol. 1978 Aug;135(2):668-74. doi: 10.1128/jb.135.2.668-674.1978.
2
Restriction enzyme cleavage map of Tn10, a transposon which encodes tetracycline resistance.Tn10的限制性内切酶切割图谱，Tn10是一种编码四环素抗性的转座子。
J Bacteriol. 1979 Jan;137(1):681-5. doi: 10.1128/jb.137.1.681-685.1979.
3
Nearly precise excision: a new type of DNA alteration associated with the translocatable element Tn10.
Cell. 1979 Apr;16(4):733-8. doi: 10.1016/0092-8674(79)90089-8.
4
Physical structures of Tn10-promoted deletions and inversions: role of 1400 bp inverted repetitions.
Cell. 1979 Apr;16(4):721-31. doi: 10.1016/0092-8674(79)90088-6.
5
DNA sequence analysis of Tn10 insertions: origin and role of 9 bp flanking repetitions during Tn10 translocation.Tn10插入的DNA序列分析：Tn10易位过程中9个碱基侧翼重复序列的起源和作用
Cell. 1979 Apr;16(4):711-20. doi: 10.1016/0092-8674(79)90087-4.
6
Overlapping divergent promoters control expression of Tn10 tetracycline resistance.重叠的反向启动子控制Tn10四环素抗性的表达。
Gene. 1983 Aug;23(2):149-56. doi: 10.1016/0378-1119(83)90046-x.
7
Organization of structural and regulatory genes that mediate tetracycline resistance in transposon Tn10.
J Bacteriol. 1979 Jun;138(3):705-14. doi: 10.1128/jb.138.3.705-714.1979.
8
Two complementation groups mediate tetracycline resistance determined by Tn10.两个互补群介导由Tn10决定的四环素抗性。
J Bacteriol. 1982 Jul;151(1):209-15. doi: 10.1128/jb.151.1.209-215.1982.
9
Identification of a second tetracycline-inducible polypeptide encoded by Tn10.Tn10编码的第二种四环素诱导型多肽的鉴定。
J Bacteriol. 1980 Oct;144(1):346-55. doi: 10.1128/jb.144.1.346-355.1980.
10
In vitro synthesis of large peptide molecules using glucosylated single-stranded bacteriophage T4D DNA template.利用糖基化单链噬菌体T4D DNA模板进行大肽分子的体外合成。
Nucleic Acids Res. 1975 Nov;2(11):2037-48. doi: 10.1093/nar/2.11.2037.

引用本文的文献

1
Bacterial resistance to the tetracyclines.细菌对四环素的耐药性。
Microbiol Rev. 1978 Dec;42(4):707-24. doi: 10.1128/mr.42.4.707-724.1978.

本文引用的文献

1
Selective binding of ribosomes to initiation sites on single-stranded DNA from bacterial viruses.核糖体与来自细菌病毒的单链DNA上起始位点的选择性结合。
Nature. 1970 Oct 17;228(5268):239-42. doi: 10.1038/228239a0.
2
Strand-specific transfer of donor DNA during conjugation in E. coli.大肠杆菌接合过程中供体DNA的链特异性转移。
Proc Natl Acad Sci U S A. 1969 May;63(1):138-43. doi: 10.1073/pnas.63.1.138.
3
Detection of an inducible membrane protein associated with R-factor-mediated tetracycline resistance.与R因子介导的四环素抗性相关的一种可诱导膜蛋白的检测。
Biochem Biophys Res Commun. 1974 Feb 27;56(4):1060-8. doi: 10.1016/s0006-291x(74)80296-2.
4
Electron microscope heteroduplex studies of sequence relations among plasmids of Escherichia coli. II. Structure of drug resistance (R) factors and F factors.大肠杆菌质粒间序列关系的电子显微镜异源双链研究。II. 耐药性（R）因子和F因子的结构
J Mol Biol. 1973 Apr 5;75(2):235-55. doi: 10.1016/0022-2836(73)90018-1.
5
Nucleotide sequence of bacteriophage phi X174 DNA.噬菌体φX174 DNA的核苷酸序列。
Nature. 1977 Feb 24;265(5596):687-95. doi: 10.1038/265687a0.
6
Ribosome-protected regions in the leader-trpE sequence of Escherichia coli tryptophan operon messenger RNA.大肠杆菌色氨酸操纵子信使核糖核酸前导序列-色氨酸E序列中的核糖体保护区域。
J Mol Biol. 1976 May 15;103(2):411-20. doi: 10.1016/0022-2836(76)90320-x.
7
Synthesis of an R plasmid protein associated with tetracycline resistance is negatively regulated.与四环素抗性相关的R质粒蛋白的合成受到负调控。
Proc Natl Acad Sci U S A. 1976 May;73(5):1509-12. doi: 10.1073/pnas.73.5.1509.
8
On the nature of tetracycline resistance controlled by the plasmid pSC101.关于由质粒pSC101控制的四环素抗性的性质。
Cell. 1978 Jan;13(1):73-81. doi: 10.1016/0092-8674(78)90139-3.
9
Physical location of ribosome binding sites on lambda DNA.
J Mol Biol. 1977 Nov;116(4):841-53. doi: 10.1016/0022-2836(77)90274-1.
10
Transcription termination at the trp operon attenuators of Escherichia coli and Salmonella typhimurium: RNA secondary structure and regulation of termination.大肠杆菌和鼠伤寒沙门氏菌色氨酸操纵子衰减子处的转录终止：RNA二级结构与终止调控
Proc Natl Acad Sci U S A. 1977 Oct;74(10):4365-9. doi: 10.1073/pnas.74.10.4365.