庆大霉素乙酰转移酶I的底物特异性及构效关系。抗生素抗性对底物Vmax/Km值的依赖性。 - Suppr

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超能文献

Substrate specificity and structure-activity relationships of gentamicin acetyltransferase I. The dependence of antibiotic resistance upon substrate Vmax/Km values.

作者信息

Williams J W, Northrop D B

出版信息

J Biol Chem. 1978 Sep 10;253(17):5908-14.

PMID:681328

Abstract

摘要

相似文献

Substrate specificity and structure-activity relationships of gentamicin acetyltransferase I. The dependence of antibiotic resistance upon substrate Vmax/Km values.庆大霉素乙酰转移酶I的底物特异性及构效关系。抗生素抗性对底物Vmax/Km值的依赖性。

J Biol Chem. 1978 Sep 10;253(17):5908-14.

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Thermodynamics of an aminoglycoside modifying enzyme with low substrate promiscuity: The aminoglycoside N3 acetyltransferase-VIa.底物选择性低的氨基糖苷修饰酶的热力学：氨基糖苷N3乙酰基转移酶-VIa

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Biosynthesis of platelet activating factor. Substrate specificity of 1-alkyl-2-lyso-sn-glycero-3-phosphocholine:acetyl-CoA acetyltransferase in rat spleen microsomes.血小板活化因子的生物合成。大鼠脾脏微粒体中1-烷基-2-溶血-sn-甘油-3-磷酸胆碱：乙酰辅酶A乙酰转移酶的底物特异性。

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Aminoglycoside resistance resulting from tight drug binding to an altered aminoglycoside acetyltransferase.由于药物与改变的氨基糖苷类乙酰转移酶紧密结合而导致的氨基糖苷类耐药性。

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Correlation of antibiotic resistance with Vmax/Km ratio of enzymatic modification of aminoglycosides by kanamycin acetyltransferase.抗生素耐药性与卡那霉素乙酰转移酶对氨基糖苷类进行酶促修饰的Vmax/Km比值之间的相关性。

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Spectrophotometric assay for amikacin using purified kanamycin acetyltransferase.使用纯化的卡那霉素乙酰转移酶对阿米卡星进行分光光度测定。

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