Boskey A L, Cohen M L, Bullough P G
Calcif Tissue Int. 1982 Jul;34(4):328-31. doi: 10.1007/BF02411262.
Formalin fixation of hard tissues alters the levels of some, but not all, of the parameters routinely measured by bone researchers. Although mineral parameters (ash weight, particle size (beta 1/2 002) and Ca/PO4 ratio) and lipid parameters (total lipid content and composition, extractability, and Ca-acidic phospholipid phosphate content) are not affected by formalin fixation, the uronate and DNA contents are reduced in formalin-fixed bone while hydroxyproline content is elevated.
硬组织的福尔马林固定会改变一些（但不是全部）骨骼研究人员常规测量参数的水平。尽管矿物质参数（灰分重量、粒度（β1/2 002）和钙/磷比率）和脂质参数（总脂质含量和组成、可提取性以及钙-酸性磷脂磷酸盐含量）不受福尔马林固定的影响，但福尔马林固定的骨骼中糖醛酸和DNA含量会降低，而羟脯氨酸含量会升高。
