Amemiya T
Klin Monbl Augenheilkd. 1982 Oct;181(4):286-9. doi: 10.1055/s-2008-1055220.
Seven patients with Basedow' disease were treated with 100 mg of indomethacin (rectal suppository) before going to bed and showed moderate improvement of various ocular disturbances. In two there was conspicuous regression of edema of the upper eyelid. In these patients a double eyelid hidden by the edema reappeared and the bloated sensation in the eyelid decreased. In two other patients, the edema and the bloated sensation in the eyelid decreased slightly. In two patients exophthalmus decreased by 1-2 mm. Diplopia disappeared in two patients and was improved in 1. Two patients failed to continue treatment with indomethacin suppositories, due to exacerbation of hemorrhoids. Indomethacin was moderately effective in treating Basedow's ophthalmopathy. The author believes that indomethacin is as efficacions as or more so than drugs tried so far for Basedow's ophthalmopathy.
7例突眼性甲状腺肿患者在睡前使用100毫克吲哚美辛（直肠栓剂）进行治疗，各种眼部不适症状有中度改善。其中2例患者上睑水肿明显消退。被水肿遮盖的双眼皮重新出现，眼睑的肿胀感减轻。另外2例患者，眼睑水肿和肿胀感略有减轻。2例患者眼球突出度下降了1 - 2毫米。2例患者复视消失，1例患者复视症状改善。2例患者因痔疮加重而未能继续使用吲哚美辛栓剂治疗。吲哚美辛在治疗突眼性甲状腺肿眼病方面有一定疗效。作者认为，吲哚美辛在治疗突眼性甲状腺肿眼病方面与目前试用过的药物效果相当或更佳。
