Vatn M H, Schrumpf E, Myren J
Scand J Gastroenterol. 1975;10(1):55-8.
Intravenous infusions of carbachol and pentagastrin were given separately or simultaneously in 6 healthy students. The volume of gastric secretion and the concentration and output of acid, pepsin, and IF increased significantly during infusion of carbachol alone, whereas the plasma gastrin concentration remained unchanged. Carbachol had no effect on the acid, pepsin, and IF secretion by pentagastrin. The results indicate an effect of carbachol on acid, pepsin, and IF secretion, independent of changes in plasma gastrin concentration. No synergistic or potentiating effect was demonstrated between carbachol and pentagastrin.
对6名健康学生分别或同时静脉输注卡巴胆碱和五肽胃泌素。单独输注卡巴胆碱期间，胃酸分泌量、酸、胃蛋白酶和内因子的浓度及分泌量显著增加，而血浆胃泌素浓度保持不变。卡巴胆碱对五肽胃泌素刺激的酸、胃蛋白酶和内因子分泌无影响。结果表明卡巴胆碱对酸、胃蛋白酶和内因子分泌有影响，且独立于血浆胃泌素浓度的变化。未证明卡巴胆碱和五肽胃泌素之间有协同或增强作用。
