Millar I B
J Epidemiol Community Health (1978). 1978 Jun;32(2):111-6. doi: 10.1136/jech.32.2.111.
Children living near a lead works and children of employees at the works were selected in order to analyse the lead content of their blood as the biological counterpart of a monitoring exercise for lead in the environment. The overall mean for the 262 children in the survey was 0.91 mumol/l and results were within the normal reference range of 0.3 to 1.8 for all except two children. The results compared favourably with similar areas, and with a survey in the same area in 1972. The mean for the 71 children of employees at the lead works was 1.02 mumol/l, significantly higher than the mean for the other children in the survey (0.88 mumol/l). No appreciable differences were found in housing or wind direction. The means for all groups were unexceptional, but some of the differences were significant. Younger children had significantly higher blood lead levels than older children, and the group of 26 children with levels of 1.3 mumol/l or more was doubly weighted with the youngest age group. After careful investigation, no deviations from normal health were found in this group. The weighting of younger children also contributed to the significance of the higher mean found for children living in the central half of the area.
为了分析儿童血液中的铅含量,以此作为环境铅监测的生物学对应指标,选取了居住在铅厂附近的儿童以及铅厂员工的子女。此次调查中262名儿童的总体平均血铅水平为0.91微摩尔/升,除两名儿童外,所有儿童的血铅水平均在0.3至1.8的正常参考范围内。与类似地区以及1972年在同一地区进行的一项调查相比,这些结果较为理想。铅厂员工的71名子女的平均血铅水平为1.02微摩尔/升,显著高于调查中其他儿童的平均水平(0.88微摩尔/升)。在住房或风向方面未发现明显差异。所有组别的平均值都属正常,但有些差异具有显著性。年幼儿童的血铅水平显著高于年长儿童,血铅水平为1.3微摩尔/升及以上的26名儿童中,年龄最小的组占比过高。经过仔细调查,该组儿童未发现与正常健康状况的偏差。年幼儿童占比过高也使得居住在该地区中部的儿童平均血铅水平较高这一结果具有显著性。