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[Effect of nootropic drugs on the dopamine release and dopamine uptake in structures of the rat striatum].

作者信息

Wustmann C, Rudolph E, Schwipper U, Ranacher B, Fischer H D, Schmidt J

出版信息

Acta Biol Med Ger. 1982;41(6):575-9.

PMID:6815946
Abstract

Nootropics increase the overflow of dopamine from rat striatum slices in a concentration dependent manner, but without relation to their clinical effectiveness. The influence of a nootropic drugs and of amphetamine on the stimulus induced dopamine release points to a relationship between nootropic and nooanaleptic activity, on the one hand, and transmitter release, on the other. Dopamine re-uptake is not altered by nootropics like piracetam.

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