• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

[利用单克隆抗体鉴定产生α干扰素的淋巴细胞群体]

[Identification of lymphocyte populations producing alpha-interferon by monoclonal antibodies].

作者信息

Lebon P, Bernard A, Boumsell L

出版信息

C R Seances Acad Sci III. 1982 Sep 20;295(2):79-82.

PMID:6816404
Abstract

Two different leucocyte populations producing alpha-interferon can be defined by monoclonal antibodies. One non glass adherent population produces interferon after induction with Herpes and Sendaï viruses. It is characterized by anti-D44 antibody, defining both some T and NK cells, but not by anti-D66 antibody with selective reactivity for T cells. The other glass adherent population is identified by OKM1 antibody, which defines about 70% of the monocytes, and can be induced only with Sendaï virus.

摘要

两种产生α-干扰素的不同白细胞群体可通过单克隆抗体来界定。一种非玻璃黏附性群体在用疱疹病毒和仙台病毒诱导后产生干扰素。其特征是抗D44抗体,该抗体可界定部分T细胞和自然杀伤细胞,但对T细胞具有选择性反应性的抗D66抗体则不能界定该群体。另一种玻璃黏附性群体由OKM1抗体识别,该抗体可界定约70%的单核细胞,且仅能由仙台病毒诱导产生。

相似文献

1
[Identification of lymphocyte populations producing alpha-interferon by monoclonal antibodies].[利用单克隆抗体鉴定产生α干扰素的淋巴细胞群体]
C R Seances Acad Sci III. 1982 Sep 20;295(2):79-82.
2
Phenotype of human alpha-interferon producing leucocytes identified by monoclonal antibodies.用单克隆抗体鉴定产生人α-干扰素的白细胞的表型。
Clin Exp Immunol. 1983 Apr;52(1):179-84.
3
A monoclonal antibody reactive with human peripheral blood monocytes.一种与人外周血单核细胞反应的单克隆抗体。
J Immunol. 1980 Apr;124(4):1943-8.
4
IL-2Ralpha-Directed monoclonal antibodies provide effective therapy in a murine model of adult T-cell leukemia by a mechanism other than blockade of IL-2/IL-2Ralpha interaction.白细胞介素-2受体α链(IL-2Rα)导向的单克隆抗体通过一种不同于阻断白细胞介素-2/白细胞介素-2受体α链(IL-2/IL-2Rα)相互作用的机制,在成人T细胞白血病小鼠模型中提供有效的治疗。
Cancer Res. 2000 Dec 15;60(24):6977-84.
5
Viral induction of low frequency interferon-alpha producing cells.病毒诱导产生低频干扰素-α的细胞
Virology. 1994 Oct;204(1):1-7. doi: 10.1006/viro.1994.1504.
6
Monoclonal antibodies to human alpha-interferon and their use for affinity chromatography.抗人α干扰素单克隆抗体及其在亲和层析中的应用。
J Immunol. 1982 Nov;129(5):2244-7.
7
Identification of T-like and B-like lymphocyte subsets in sea star Asterias rubens by monoclonal antibodies to human leukocytes.利用抗人白细胞单克隆抗体鉴定海星红斑海盘车中的T样和B样淋巴细胞亚群。
Thymus. 1993 May;21(3):133-9.
8
Phenotypes of human natural killer cell populations detected with monoclonal antibodies.用单克隆抗体检测的人类自然杀伤细胞群体的表型
J Immunol. 1981 Dec;127(6):2575-80.
9
Increase in tumor necrosis factor-alpha mRNA but not perforin mRNA expression in response to two newly characterized anti-LFA-1 monoclonal antibodies.对两种新鉴定的抗淋巴细胞功能相关抗原-1单克隆抗体的应答中,肿瘤坏死因子-α信使核糖核酸表达增加,但穿孔素信使核糖核酸表达未增加。
Nat Immun. 1994 Nov-Dec;13(6):301-14.
10
Determination of surface antigens on highly purified human NK cells by flow cytometry with monoclonal antibodies.利用单克隆抗体通过流式细胞术测定高度纯化的人自然杀伤细胞表面抗原。
J Immunol. 1981 Dec;127(6):2401-9.

引用本文的文献

1
Human natural interferon-alpha producing cells.人类天然产生α干扰素的细胞。
Pharmacol Ther. 1993 Oct;60(1):39-62. doi: 10.1016/0163-7258(93)90021-5.
2
Interferon-alpha production and tissue localization of interferon-alpha/beta producing cells after intradermal administration of Aujeszky's disease virus-infected cells in pigs.猪皮内接种伪狂犬病病毒感染细胞后α干扰素的产生及α/β干扰素产生细胞的组织定位
Scand J Immunol. 1995 Feb;41(2):121-9. doi: 10.1111/j.1365-3083.1995.tb03543.x.
3
Synthesis of intrathecal interferon in systemic lupus erythematosus with neurological complications.
伴有神经并发症的系统性红斑狼疮患者鞘内干扰素的合成
Br Med J (Clin Res Ed). 1983 Oct 22;287(6400):1165-7. doi: 10.1136/bmj.287.6400.1165.
4
Dendritic cells and IFN-alpha-producing cells are two functionally distinct non-B, non-monocytic HLA-DR+ cell subsets in human peripheral blood.树突状细胞和产生干扰素-α的细胞是人类外周血中两个功能不同的非B、非单核细胞的HLA-DR+细胞亚群。
Immunology. 1989 Dec;68(4):486-90.
5
Characterization of blood mononuclear cells producing IFN alpha following induction by coronavirus-infected cells (porcine transmissible gastroenteritis virus).冠状病毒感染细胞(猪传染性胃肠炎病毒)诱导后产生干扰素α的血液单核细胞的特性分析。
Res Immunol. 1990 Feb;141(2):141-51. doi: 10.1016/0923-2494(90)90133-j.
6
Glycosylation is required for coronavirus TGEV to induce an efficient production of IFN alpha by blood mononuclear cells.冠状病毒TGEV诱导血液单核细胞高效产生α干扰素需要糖基化。
Scand J Immunol. 1991 Apr;33(4):435-40. doi: 10.1111/j.1365-3083.1991.tb01792.x.
7
Single amino acid changes in the viral glycoprotein M affect induction of alpha interferon by the coronavirus transmissible gastroenteritis virus.病毒糖蛋白M中的单个氨基酸变化会影响冠状病毒传染性胃肠炎病毒诱导α干扰素的能力。
J Virol. 1992 Feb;66(2):743-9. doi: 10.1128/JVI.66.2.743-749.1992.