Abel B J, Carswell G, Elton R, Hargreave T B, Kyle K, Orr S, Rogers A, Baxby K, Yates A
Br J Urol. 1982 Dec;54(6):780-4. doi: 10.1111/j.1464-410x.1982.tb13647.x.
A prospective randomised trial was carried out to assess the effect of 6 months' treatment with either clomiphene citrate or vitamin C in 179 men complaining of infertile marriage. There was no significant difference in the wife's pregnancy rates between the 2 treatment groups. In order to detect a subgroup that might respond to clomiphene the results were analysed according to pre-treatment FSH and sperm density, with allowance being made for the result of the wife's tests, but still there was no significant difference in treatment response Vitamin C would seem a preferable and cheaper alternative treatment for male infertility.
一项前瞻性随机试验对179名抱怨不育的男性进行了为期6个月的枸橼酸氯米芬或维生素C治疗，以评估其效果。两个治疗组妻子的妊娠率没有显著差异。为了检测可能对氯米芬有反应的亚组，根据治疗前的促卵泡生成素（FSH）和精子密度对结果进行了分析，并考虑了妻子的检测结果，但治疗反应仍无显著差异。对于男性不育症，维生素C似乎是一种更可取且更便宜的替代治疗方法。
