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犬支原体:与犬瘟热肺炎相关的支原体致病性

Canine mycoplasmas: pathogenicity of mycoplasmas associated with distemper pneumonia.

作者信息

Rosendal S

出版信息

J Infect Dis. 1978 Aug;138(2):203-10. doi: 10.1093/infdis/138.2.203.

DOI:10.1093/infdis/138.2.203
PMID:681796
Abstract

Mycoplasmas of the following species were isolated from the lungs of dog with distemper: Mycoplasma cynos, Mycoplasma bovigenitalium, Mycoplasma canis, Mycoplasma spumans, and Mycoplasma gateae. One-week-old dogs were inoculated endobronchially with cloned cultures of each species. M. cynos induced a focal pneumonia that were characterized histologically by severe inflammation of bronchi and adjacent respiratory tract tissue. The inflammatory response was initially neutrophilic and later was histiocytic with interstitial lymphoid hyperplasia. M. cynos was recovered from the lungs of inoculated dogs until three weeks after inoculation. A mild inflammatory response was observed in lung tissue of the dog inoculated with M. bovigenitalium, whereas M. canis, M. spumans, and, M. gateae did not induce any visible lesions.

摘要

从患有犬瘟热的犬类肺部分离出了以下几种支原体

犬支原体、牛生殖支原体、犬支原体、泡沫支原体和加氏支原体。对一周龄的幼犬进行支气管内接种每种支原体的克隆培养物。犬支原体引发了局灶性肺炎,组织学特征为支气管和相邻呼吸道组织的严重炎症。炎症反应最初是中性粒细胞性的,后来是组织细胞性的,并伴有间质淋巴样增生。在接种后三周内,均可从接种犬的肺部分离出犬支原体。接种牛生殖支原体的犬肺组织中观察到轻度炎症反应,而犬支原体、泡沫支原体和加氏支原体未引起任何可见病变。

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