Gourlay R N, Howard C J, Thomas L H, Wyld S G
Res Vet Sci. 1979 Sep;27(2):233-7.
Cloned cultures of 16 strains, representing nine different species of Mycoplasma and Acholeplasma, were inoculated intratracheally into gnotobiotic calves. Strains of M bovirhinis, M canadense, M verecundum, A axanthum and A modicum did not produce visible pneumonic lesions and were not reisolated from the lungs. Strains of M alkalescens and M arginini colonised the lower respiratory tract but failed to produce visible pneumonia. M bovigenitalium (strain M991/70) and M dispar (strain Gri226) both colonised the respiratory tract and induced pneumonic lesions estimated to involve up to 8 per cent (M bovigenitalium) and 17 per cent (M dispar) of the lung. Histologically M bovigenitalium produced a cuffing pneumonia and M dispar produced a interstitial alveolitis.
将代表9种不同支原体和无胆甾原体的16个菌株的克隆培养物经气管内接种到无菌犊牛体内。牛鼻支原体、加拿大支原体、羞怯支原体、无色无胆甾原体和少量无胆甾原体菌株未产生明显的肺部病变，且未从肺部分离出来。碱性支原体和精氨酸支原体菌株定殖于下呼吸道，但未产生明显的肺炎。牛生殖支原体（菌株M991/70）和差异支原体（菌株Gri226）均定殖于呼吸道，并诱发了肺部病变，估计牛生殖支原体累及肺部的8%，差异支原体累及17%。组织学上，牛生殖支原体引起套袖状肺炎，差异支原体引起间质性肺泡炎。
