Amet Y, Abalain J H, Daniel J Y, Thieulant M L, Floch H H
C R Seances Acad Sci III. 1982 Nov 15;295(9):523-8.
5 alpha-DHT is bound with a high affinity (Kd = 0.8 nM) and a limited capacity (80 fmol/mg proteins) in the cytosol of the preen gland of quails, an analogue of sebaceous glands. The complex can be precipitated by protamin-sulfate and is sedimented in the 8 S region after ultra-centrifugation in a sucrose gradient. The occurrence of this binding that exhibits the main properties of an androgen receptor, supports the use of the preen gland of quails as a tool for the study of the mechanism of action of androgens in birds and as a model for the study of the androgen control of sebaceous-like glands.
5α - 双氢睾酮以高亲和力（解离常数Kd = 0.8纳摩尔）和有限容量（80飞摩尔/毫克蛋白质）与鹌鹑泄殖腔腺（皮脂腺的类似物）的胞质溶胶结合。该复合物可被硫酸鱼精蛋白沉淀，并在蔗糖梯度中超速离心后沉降在8S区域。这种具有雄激素受体主要特性的结合的存在，支持将鹌鹑泄殖腔腺用作研究雄激素在鸟类中作用机制的工具以及研究雄激素对皮脂腺样腺体控制的模型。
