Wahlgren N G, Kjellin K G, Söderström C E
J Neurol Sci. 1978 Jul;37(3):215-25. doi: 10.1016/0022-510x(78)90205-8.
Combined examinations with quantitative CSF spectrophotometry (CSF-SPE) and computer tomography (CT) were performed on 53 patients with traumatic head injuries. In cerebral concussion the results were mainly normal in both examinations. In cerebral contusion bleeding patterns were found by CSF-SPE in all subjects, with a special bleeding pattern (S2 pattern) occurring in 86%. CT showed findings described as typical for contusion in 8 of 14 examined patients, the remaining CT scans showing questionable or normal signs. In extra- and intracerebral haematomas, all patients had bleeding patterns on the CSF-SPE. A special bleeding component (H factor) was found in about 72%. The H component was not observed during the first 3 to 4 days after the trauma. All but one patient examined later than the 4th day had an H component with or without an S-pattern. CT demonstrated a haematoma in 14 of 18 verified haematoma patients, while 4 subjects with subdural haematoma (e.g. one third of this group) had questionable CT findings. The combined examinations with CT and CSF-SPE, being complementary to each other, are of great value in the different diagnosis of traumatic head injuries.
对53例颅脑外伤患者进行了脑脊液定量分光光度法(CSF-SPE)和计算机断层扫描(CT)联合检查。在脑震荡患者中,两项检查结果大多正常。在脑挫裂伤患者中,通过CSF-SPE在所有受试者中均发现出血模式,其中86%出现特殊出血模式(S2模式)。在14例接受检查的患者中,CT显示有8例有典型的挫裂伤表现,其余CT扫描显示有可疑或正常征象。在脑内和脑外血肿患者中,所有患者的CSF-SPE均有出血模式。约72%发现有特殊出血成分(H因子)。在创伤后的最初3至4天内未观察到H成分。除1例患者外,所有在第4天后接受检查的患者均有H成分,伴有或不伴有S模式。在18例经证实的血肿患者中,CT显示有14例存在血肿,而4例硬膜下血肿患者(占该组的三分之一)的CT表现可疑。CT和CSF-SPE联合检查相互补充,在颅脑外伤的鉴别诊断中具有重要价值。