糖尿病小瞳孔中神经病变病因的证据。
Evidence for a neuropathic aetiology in the small pupil of diabetes mellitus.
作者信息
Smith S A, Smith S E
出版信息
Br J Ophthalmol. 1983 Feb;67(2):89-93. doi: 10.1136/bjo.67.2.89.
Abstract
Infrared television pupillometry was performed on 34 insulin-treated diabetic patients and 55 healthy subjects. Sixteen of the diabetic patients had pupils that failed to dilate normally in darkness. The occurrence of a small pupil was associated with cardiac vagal dysfunction and somatic sensory loss. The small pupil was found to be supersensitive to the mydriatic effect of topical 2% phenylephrine but normally sensitive to 0.5% hydroxyamphetamine eyedrops. It is concluded that the failure of the pupil to dilate in darkness in some diabetic patients is due to neuropathy of the sympathetic innervation.
摘要
对34例接受胰岛素治疗的糖尿病患者和55名健康受试者进行了红外电视瞳孔测量。16例糖尿病患者的瞳孔在黑暗中不能正常扩大。小瞳孔的出现与心脏迷走神经功能障碍和躯体感觉丧失有关。发现小瞳孔对局部使用2%去氧肾上腺素的散瞳作用超敏感，但对0.5%羟苯丙胺滴眼液正常敏感。得出结论，一些糖尿病患者在黑暗中瞳孔不能扩大是由于交感神经支配的神经病变。
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本文引用的文献
1
Supersensitivity and subsensitivity to sympathomimetic amines.对拟交感胺的超敏反应和低敏反应。
Pharmacol Rev. 1963 Jun;15:225-76.
2
Evaluation of the causes and accuracy of pharmacologic localization in Horner's syndrome.霍纳综合征中药物定位的原因及准确性评估。
Am J Ophthalmol. 1980 Sep;90(3):394-402. doi: 10.1016/s0002-9394(14)74924-4.
3
Heart rate variability in healthy subjects measured with a bedside computer-based technique.采用基于床边计算机技术测量健康受试者的心率变异性。
Clin Sci (Lond). 1981 Oct;61(4):379-83. doi: 10.1042/cs0610379.
4
Micro-column method for HbA1 determination.
Lancet. 1980 May 24;1(8178):1114-6. doi: 10.1016/s0140-6736(80)91557-3.
5
The interactions of local guanethidine and sympathomimetic amines in the human eye.胍乙啶与拟交感神经胺在人眼中的相互作用。
Arch Ophthalmol. 1969 May;81(5):622-7. doi: 10.1001/archopht.1969.00990010624005.
6
7
Adrenergic denervation supersensitivity.肾上腺素能去神经超敏反应
Adv Neurol. 1975;9:113-20.
8
Sympathetic pupillary tone in old age.老年人的交感神经瞳孔张力。
Arch Ophthalmol. 1976 Nov;94(11):1905-6. doi: 10.1001/archopht.1976.03910040615006.
9
Diagnosing Horner's syndrome.
Trans Sect Ophthalmol Am Acad Ophthalmol Otolaryngol. 1977 Sep-Oct;83(5):840-2.
10
[Diabetes mellitus and its degenerative complications: a prospective study of 4,400 patients observed between 1947 and 1973 (author's transl)].
Diabete Metab. 1977 Jun;3(2):97-107.
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