Smith S A, Smith S E
Br J Ophthalmol. 1983 Feb;67(2):89-93. doi: 10.1136/bjo.67.2.89.
Infrared television pupillometry was performed on 34 insulin-treated diabetic patients and 55 healthy subjects. Sixteen of the diabetic patients had pupils that failed to dilate normally in darkness. The occurrence of a small pupil was associated with cardiac vagal dysfunction and somatic sensory loss. The small pupil was found to be supersensitive to the mydriatic effect of topical 2% phenylephrine but normally sensitive to 0.5% hydroxyamphetamine eyedrops. It is concluded that the failure of the pupil to dilate in darkness in some diabetic patients is due to neuropathy of the sympathetic innervation.
对34例接受胰岛素治疗的糖尿病患者和55名健康受试者进行了红外电视瞳孔测量。16例糖尿病患者的瞳孔在黑暗中不能正常扩大。小瞳孔的出现与心脏迷走神经功能障碍和躯体感觉丧失有关。发现小瞳孔对局部使用2%去氧肾上腺素的散瞳作用超敏感,但对0.5%羟苯丙胺滴眼液正常敏感。得出结论,一些糖尿病患者在黑暗中瞳孔不能扩大是由于交感神经支配的神经病变。