Smith S A, Dewhirst R R
Diabet Med. 1986 Jan;3(1):38-41. doi: 10.1111/j.1464-5491.1986.tb00703.x.
A simple portable pupillometer using Polaroid photography has been developed for use in the diagnosis of diabetic autonomic neuropathy. The pupil diameter per cent (PD%), defined as the percentage of iris diameter to which pupil diameter had dilated in darkness, was measured from the instant colour prints. An age-related normal range was constructed from measurements in 163 healthy subjects in whom PD% declined linearly by 3% per decade. The PD% was measured in 15 patients with automatic neuropathy and 12 were identified with abnormally low values indicating a failure of sympathetically mediated dilatation. Results were consistent with the standard television pupillometric technique and had the same high repeatability with a coefficient of variation of 3.2%.
一种使用宝丽来摄影技术的简易便携式瞳孔计已被开发出来用于诊断糖尿病性自主神经病变。瞳孔直径百分比（PD%）定义为在黑暗中瞳孔直径扩张至虹膜直径的百分比，通过即时彩色照片进行测量。根据对163名健康受试者的测量构建了与年龄相关的正常范围，其中PD%每十年线性下降3%。对15例患有自主神经病变的患者进行了PD%测量，其中12例被确定为值异常低，表明交感神经介导的瞳孔扩张功能障碍。结果与标准电视瞳孔测量技术一致，具有相同的高重复性，变异系数为3.2%。
