Bozzetti F, Nava M, Bufalino R, Menotti V, Marolda R, Doci R, Gennari L
Dis Colon Rectum. 1983 Jan;26(1):25-9. doi: 10.1007/BF02554674.
Early surgical complications following colostomy closure in 65 cancer patients operated on at the Istituto Nazionale Tumori of Milan were evaluated retrospectively. The overall complication rate was 24.6 per cent, including infections (13.8 per cent), fistulas (6.1 per cent), wound dehiscence (3.0 per cent), and distal stenosis (1.5 per cent). Type and rate of complications were analyzed to find a correlation with type, site, and location of colostomy, technique of closure, presence or absence of drains, or time interval between construction and closure of colostomy. No statistically significant association between the aforementioned factors and occurrence and rate of complications was found. The authors think, therefore, that surgical attention, including meticulous manipulation of the stoma, avoidance of contamination of the wound, tension of sutures, dead spaces, and collection of blood in the wound, and use of antibiotics and antiseptics are the most important principles to minimize postoperative complications.
对在米兰国家肿瘤研究所接受手术的65例癌症患者结肠造口关闭术后的早期手术并发症进行了回顾性评估。总体并发症发生率为24.6%，包括感染（13.8%）、瘘管（6.1%）、伤口裂开（3.0%）和远端狭窄（1.5%）。分析并发症的类型和发生率，以寻找与结肠造口的类型、部位和位置、关闭技术、引流管的有无或结肠造口构建与关闭之间的时间间隔的相关性。未发现上述因素与并发症的发生和发生率之间存在统计学上的显著关联。因此，作者认为，手术注意事项，包括对造口的细致操作、避免伤口污染、缝线张力、死腔以及伤口内积血，以及使用抗生素和防腐剂，是将术后并发症降至最低的最重要原则。
