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保护性结肠造口关闭术:一项“小”手术的风险

Protective colostomy closure: the hazards of a "minor" operation.

作者信息

Altomare D F, Pannarale O C, Lupo L, Palasciano N, Memeo V, Rubino M

机构信息

Institute of Clinical Surgery, University of Bari, Italy.

出版信息

Int J Colorectal Dis. 1990 May;5(2):73-8. doi: 10.1007/BF00298472.

Abstract

A retrospective study of 87 patients, subjected to colostomy closure between 1976 and 1987, was conducted in order to evaluate the role of 8 potential risk factors on morbidity and mortality. Possible risk factors were age greater than 65 years, presence of hypoalbuminaemia (less than 3.0 gr%), anaemia (Hb less than 10 gr%), operative technique, duration of colostomy, site of colostomy, underlying disease and presence of subcutaneous drainage. Apart from hypoalbuminaemia, no clear risk factor was identified, although an interval of more than 90 days between construction and closure of colostomy appears to be safer than shorter intervals. A comparison was also made between two different periods from 1976 to 1982 and from 1983 to 1987 which resulted in important changes in patient management in the second period including: type of antibiotic prophylaxis, type of anastomosis and suture material, site of colostomy and mean duration of colostomy. Four post-operative deaths (4.6%) (two for myocardial insufficiency and two for sepsis), 11 major (13%) and 25 (29%) minor complications were recorded. The analysis of the two different periods showed a strong reduction in both mortality and morbidity in the second period, which could be related to a better management of this type of patient. In conclusion, the incidence of mortality and morbidity in colostomy closure cannot be underestimated and therefore the same skill and meticulous approach are required for this operation as for any major surgical procedure on the colon.

摘要

对1976年至1987年间接受结肠造口关闭术的87例患者进行了一项回顾性研究,以评估8种潜在风险因素对发病率和死亡率的影响。可能的风险因素包括年龄大于65岁、存在低白蛋白血症(低于3.0克%)、贫血(血红蛋白低于10克%)、手术技术、结肠造口持续时间、结肠造口部位、基础疾病以及是否存在皮下引流。除低白蛋白血症外,未发现明确的风险因素,尽管结肠造口造口与关闭之间间隔超过90天似乎比间隔较短更安全。还对1976年至1982年以及1983年至1987年这两个不同时期进行了比较,结果发现第二个时期患者管理发生了重大变化,包括:抗生素预防类型、吻合方式和缝合材料类型、结肠造口部位以及结肠造口平均持续时间。记录了4例术后死亡(4.6%)(2例死于心肌功能不全,2例死于败血症)、11例严重并发症(13%)和25例(29%)轻微并发症。对两个不同时期的分析表明,第二个时期的死亡率和发病率均大幅降低,这可能与对这类患者的更好管理有关。总之,结肠造口关闭术的死亡率和发病率不容忽视,因此该手术需要与结肠的任何大型外科手术一样的技能和细致方法。

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