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血液系统疾病中的肝紫癜病。两例报告。

Peliosis hepatis in hematologic disease. Report of two cases.

作者信息

Chopra S, Edelstein A, Koff R S, Zimelman A P, Lacson A, Neiman R S

出版信息

JAMA. 1978 Sep 8;240(11):1153-5.

PMID:682289
Abstract

Two patients with hematologic disease, one of whom had received androgenic steroids, had liver damage associated with peliosis hepatis. In one patient with spherocytic hemolytic anemia, peliosis hepatis was an incidental postmortem finding. In the other patient, who was treated with androgenic-anabolic steroids for aplastic anemia, hepatic failure associated with peliosis hepatis developed. Splenic involvement by peliosis was present in both patients. Peliosis hepatis should be considered in the differential diagnosis of hepatic disease in patients with hematologic disorders, especially if treatment has included androgenic-anabolic steroids.

摘要

两名血液病患者,其中一名曾接受雄激素类甾体治疗,出现与肝紫癜相关的肝损伤。在一名球形红细胞溶血性贫血患者中,肝紫癜是尸检时偶然发现的。另一名因再生障碍性贫血接受雄激素 - 合成代谢类甾体治疗的患者,发生了与肝紫癜相关的肝衰竭。两名患者均有脾脏受累于紫癜的情况。对于血液系统疾病患者的肝病鉴别诊断,应考虑肝紫癜,尤其是在治疗中使用过雄激素 - 合成代谢类甾体的情况下。

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Peliosis hepatis in hematologic disease. Report of two cases.血液系统疾病中的肝紫癜病。两例报告。
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A case of intra-abdominal hemorrhage secondary to peliosis hepatis.1例肝紫癜病继发腹腔内出血。
Int J Surg Case Rep. 2015;7C:47-50. doi: 10.1016/j.ijscr.2014.12.030. Epub 2014 Dec 30.
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Drug-induced liver injury: is it somehow foreseeable?药物性肝损伤:在某种程度上可以预见吗?
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Peliosis of the spleen: possible association with chronic renal failure and erythropoietin therapy.脾脏紫癜症:可能与慢性肾衰竭及促红细胞生成素治疗有关。
Postgrad Med J. 1995 Aug;71(838):493-6. doi: 10.1136/pgmj.71.838.493.
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Peliosis hepatis induced by 6-thioguanine administration.6-硫鸟嘌呤给药诱导的肝紫癜
Gut. 1988 Sep;29(9):1265-9. doi: 10.1136/gut.29.9.1265.
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Hepatocellular carcinoma and focal nodular hyperplasia associated with norethandrolone-therapy: a case report.
Blut. 1986 Feb;52(2):111-6. doi: 10.1007/BF00321073.