Achauer B M
Plast Reconstr Surg. 1983 Feb;71(2):251-4. doi: 10.1097/00006534-198302000-00020.
A serious complication following MDX4-4011 Dow-Corning silicone for injection to the face is reported. The patient developed inflammatory lesions 11 years after her last silicone injection for what was felt to be Weber-Christian disease. The patient also had a diagnosis of rheumatoid arthritis and a questionable history of mycoplasm infection. She eventually required excision of the right facial area with flap reconstruction. There is at least one other investigator who has had inflammatory complications following silicone injection to a patient with Weber-Christian disease. For these reasons, caution in using liquid silicone in patients who might have Weber-Christian disease is recommended.
据报道，注射用MDX4 - 4011道康宁硅胶用于面部后出现了严重并发症。该患者在最后一次注射硅胶11年后出现炎性病变，当时认为是韦格纳-克里斯蒂安病。该患者还被诊断患有类风湿性关节炎，并有支原体感染的可疑病史。她最终需要切除右侧面部区域并进行皮瓣重建。至少还有一名研究者在给一名患有韦格纳-克里斯蒂安病的患者注射硅胶后出现了炎性并发症。基于这些原因，建议在可能患有韦格纳-克里斯蒂安病的患者中谨慎使用液体硅胶。
