Rapaport M J, Vinnik C, Zarem H
Los Angeles, California, USA.
Aesthetic Plast Surg. 1996 May-Jun;20(3):267-76. doi: 10.1007/s002669900032.
Fifty-four patients with problems following "medical grade" silicone injections into the face and legs were seen from 1974 until 1995. Complications consisted of chronic cellulitis, nodules, foreign body reactions, and movement of material to near and distant parts of the body. These difficulties usually demonstrated themselves many years after injection. It is suggested that problems occur despite good technique, good material, and small amounts injected. Because the side effects are unpredictable and often uncorrectable, further studies must be performed to insure silicone's safety.
1974年至1995年期间，共诊治了54例在面部和腿部注射“医用级”硅胶后出现问题的患者。并发症包括慢性蜂窝织炎、结节、异物反应以及材料向身体近远端部位的移动。这些问题通常在注射多年后才显现出来。研究表明，即使注射技术良好、使用优质材料且注射量小，仍会出现问题。由于副作用不可预测且往往无法纠正，必须进行进一步研究以确保硅胶的安全性。
