Slattery P J, Harmer M, Rosen M, Vickers M D
Ann R Coll Surg Engl. 1983 Jan;65(1):18-9.
Patients receiving staff-administered analgesics after upper abdominal surgery had higher pain scores than similar patients having self-administered analgesics, but this was associated with a considerably smaller average amount of analgesic given. This survey was subject to observer and patient bias and it was necessary to use 'pethidine equivalents' to enable comparisons to be made between drugs with effects of different duration; thus the striking differences in pain scores and grades can be considered indicative only. They nevertheless support the continued investigation of on-demand systems and make a strong case for a double-blind controlled trial.
接受医护人员给予镇痛药的上腹部手术后患者，其疼痛评分高于自行给药的类似患者，但这与给予的镇痛药平均量显著较少有关。这项调查存在观察者和患者偏倚，有必要使用“哌替啶等效剂量”以便能够对作用持续时间不同的药物进行比较；因此，疼痛评分和等级的显著差异只能视为指示性的。然而，它们支持对按需给药系统继续进行研究，并有力地说明了进行双盲对照试验的必要性。
