长期视网膜静脉阻塞患者的血液粘度和止血异常。
Abnormal blood viscosity and haemostasis in long-standing retinal vein occlusion.
作者信息
Trope G E, Lowe G D, McArdle B M, Douglas J T, Forbes C D, Prentice C M, Foulds W S
出版信息
Br J Ophthalmol. 1983 Mar;67(3):137-42. doi: 10.1136/bjo.67.3.137.
Abstract
Blood viscosity and several haemostatic factors were measured in 42 patients with long-standing retinal vein occlusion and 33 control subjects. Blood viscosity, haematocrit, plasma viscosity, fibrinogen, fibrinopeptide A, and beta-thromboglobulin were increased in the 20 subjects with capillary nonperfusion or new vessels, but not in the 22 subjects without these complications. Patients with nonperfusion or new vessels also had a lower platelet count than patients without complications. Increased levels of factor VIII antigen and decreased levels of antithrombin III were found in the retinal vein occlusion group as a whole. These findings suggest that blood viscosity, platelets, and coagulation may be involved in retinal vein occlusion and its vascular complications.
摘要
对42例长期视网膜静脉阻塞患者和33名对照者进行了血液粘度和多项止血因子检测。在20例存在毛细血管无灌注或新生血管的患者中，血液粘度、血细胞比容、血浆粘度、纤维蛋白原、纤维肽A和β-血小板球蛋白升高，但在22例无这些并发症的患者中未升高。有毛细血管无灌注或新生血管的患者血小板计数也低于无并发症的患者。视网膜静脉阻塞组整体上因子VIII抗原水平升高，抗凝血酶III水平降低。这些发现提示血液粘度、血小板和凝血可能与视网膜静脉阻塞及其血管并发症有关。
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