Dodson P M, Westwick J, Marks G, Kakkar V V, Galton D J
Br J Ophthalmol. 1983 Mar;67(3):143-6. doi: 10.1136/bjo.67.3.143.
Fifty-six patients with retinal vein occlusion--35 with central and 21 with branch vein occlusion--were investigated for comparison with an age and sex matched control group. Mean levels of beta-thromboglobulin and platelet factor 4 were significantly higher (p less than 0.001) in both the group with central and the group with branch retinal vein occlusion than in the control group. A significant increase of beta-thromboglobulin (p less than 0.001) was also found in the retinal vein occlusion group in those patients who were not hyperlipidaemic or diabetic (n = 39). Weak correlations were found between levels of lipoprotein cholesterol and plasma beta-thromboglobulin. Increased platelet aggregation may contribute to the aetiology of retinal vein occlusion.
对56例视网膜静脉阻塞患者（35例为中央静脉阻塞，21例为分支静脉阻塞）进行了研究，以与年龄和性别匹配的对照组进行比较。中央视网膜静脉阻塞组和分支视网膜静脉阻塞组的β-血小板球蛋白和血小板因子4的平均水平均显著高于对照组（p<0.001）。在非高脂血症或糖尿病患者（n = 39）的视网膜静脉阻塞组中也发现β-血小板球蛋白显著升高（p<0.001）。脂蛋白胆固醇水平与血浆β-血小板球蛋白之间存在弱相关性。血小板聚集增加可能有助于视网膜静脉阻塞的病因学。
