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电刺激和卡巴胆碱点燃的双向传递

Bidirectional transfer of electrical and carbachol kindling.

作者信息

Cain D P

出版信息

Brain Res. 1983 Jan 31;260(1):135-8. doi: 10.1016/0006-8993(83)90774-6.

DOI:10.1016/0006-8993(83)90774-6
PMID:6824951
Abstract

In two experiments rats were kindled by electrical stimulation or the infusion of carbachol, and subsequently rekindled by carbachol or electrical stimulation, respectively, in the amygdala. The rats that previously had been kindled using one agent kindled significantly faster and displayed significantly stronger seizures when rekindled using the other agent. These results are consistent with the idea that cholinoceptive neurons may normally participate in electrical kindling of the amygdala although such participation does not appear to be crucial.

摘要

在两项实验中,通过电刺激或注入卡巴胆碱使大鼠杏仁核点燃,随后分别用卡巴胆碱或电刺激使其再次点燃。先前用一种试剂点燃的大鼠,在用另一种试剂再次点燃时,点燃速度明显更快,癫痫发作也明显更强。这些结果与以下观点一致,即胆碱能感受神经元可能通常参与杏仁核的电点燃过程,尽管这种参与似乎并非至关重要。

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