Brandstetter R D, Gotz V P
Drug Intell Clin Pharm. 1983 Feb;17(2):125-6. doi: 10.1177/106002808301700208.
A patient who developed phlebitis from the intravenous administration of diazepam is described. This episode resolved in two days after treatment with moist heat packs. Three days after complete resolution, the phlebitis recurred approximately eight hours after a single oral dose of diazepam. This recurrence of phlebitis resolved slowly over seven days, with warm soaking and aspirin therapy. Oral diazepam may have exacerbated the initial phlebitis by interfering with a subclinical healing process.
描述了一名因静脉注射地西泮而发生静脉炎的患者。经湿热敷治疗后，该症状在两天内得到缓解。完全缓解三天后，在单次口服地西泮约八小时后静脉炎复发。经热敷和阿司匹林治疗，此次静脉炎复发在七天内缓慢消退。口服地西泮可能通过干扰亚临床愈合过程而加重了最初的静脉炎。
