焦炉工人淋巴细胞姐妹染色单体交换（SCE）频率

Lymphocyte sister chromatid exchange (SCE) frequencies in coke oven workers.

作者信息

Miner J K, Rom W N, Livingston G K, Lyon J L

出版信息

J Occup Med. 1983 Jan;25(1):30-3. doi: 10.1097/00043764-198301000-00012.

DOI:10.1097/00043764-198301000-00012

Abstract

Lymphocyte sister chromatid exchange (SCE) frequencies were determined for 12 long-term coke oven workers and 12 other age-matched steelworkers with no coke oven work exposure. All study participants were nonsmokers. The exposed group had a mean of 28.9 years' exposure to the coke oven emissions. SCE frequencies for the exposed individuals ranged from 7.97 to 11.20 SCEs per cell while the control individuals ranged from 6.73 to 10.60 SCEs per cell. The mean SCE frequency for the exposed group was 9.54 +/- SD 1.15 SCEs per cell, and was 14% higher than the 8.35 +/- SD 1.09 SCEs per cell of the control group (p = .016). The long-term exposure to coke oven emissions experienced by the coke oven workers may be the explanation for this small difference.

摘要

测定了12名长期从事炼焦炉工作的工人以及12名年龄匹配、无炼焦炉工作接触史的其他钢铁工人的淋巴细胞姐妹染色单体交换（SCE）频率。所有研究参与者均不吸烟。暴露组平均有28.9年的炼焦炉排放物接触史。暴露个体的SCE频率为每细胞7.97至11.20次SCE，而对照个体为每细胞6.73至10.60次SCE。暴露组的平均SCE频率为每细胞9.54±标准差1.15次SCE，比对照组每细胞8.35±标准差1.09次SCE高14%（p = 0.016）。炼焦炉工人长期接触炼焦炉排放物可能是造成这一微小差异的原因。