Prochnow F, Tapolcsányi L
Langenbecks Arch Chir. 1978 Aug 18;346(2):109-17. doi: 10.1007/BF01261397.
Between 1950 and 1960, 118 partial mastectomies in the treatment of early breast cancer have been carried out in four different techniques with block dissection and radiotherapy. The 5-10-15 year survivals were compared to a similar selection of 217 patients with radical operations. No significant differences could be found between the 5 and 10 years survival rates, but the number of patients living longer than 15 years is much higher following radical operation chiefly in the cases with stage II. It is probably caused by the double frequency of local recidives following partial mastectomy, and after their treatment no patients survived to the 15th year. Partial mastectomy is no routine procedure. It is carried out when the patient refuses radical operation. The partial mastectomy should be the subject of a controlled clinical study.
1950年至1960年间，采用四种不同技术并结合淋巴结清扫和放疗对118例早期乳腺癌患者实施了局部乳房切除术。将这些患者的5年、10年和15年生存率与另外217例接受根治性手术的类似患者进行了比较。5年和10年生存率之间未发现显著差异，但根治性手术后存活超过15年的患者数量要多得多，主要是II期患者。这可能是由于局部乳房切除术后局部复发率是根治性手术的两倍，且复发后接受治疗的患者无一人存活至第15年。局部乳房切除术并非常规手术。仅在患者拒绝根治性手术时才实施。局部乳房切除术应作为一项对照临床研究的课题。
