Altman H S, Phillips G, Bank S, Klotz H
Am J Gastroenterol. 1983 Mar;78(3):174-7.
The fourth reported patient with acute pancreatitis associated with Crohn's disease of the duodenum is presented and the clinical features compared with previously described cases. The pathogenesis of the pancreatitis was not clear but the inflammatory process was found to involve the ampulla of Vater making ampullary incompetence with duodenal reflux or ampullary obstruction the most likely mechanisms. High dose prednisone combined with nasogastric suction and subsequently long-term Cimetidine resulted in a rapid improvement which has been maintained.
本文报告了第四例与十二指肠克罗恩病相关的急性胰腺炎患者，并将其临床特征与先前描述的病例进行了比较。胰腺炎的发病机制尚不清楚，但发现炎症过程累及 Vater 壶腹，使壶腹功能不全伴十二指肠反流或壶腹梗阻成为最可能的机制。大剂量泼尼松联合鼻胃管吸引，随后长期使用西咪替丁，病情迅速改善并得以维持。
