Walgenbach S C, Donald D E
Am J Physiol. 1983 Mar;244(3):H362-9. doi: 10.1152/ajpheart.1983.244.3.H362.
Mean arterial blood pressure, heart rate, and cardiac output were monitored at rest and during exercise of two grades of severity in conscious dogs under control conditions and after progressive interruption of the baroreflexes. Aortic arch denervation and vascular isolation and pressurization of the carotid sinuses were used to interrupt arterial baroreflexes. Subsequent interruption of cardiopulmonary afferents was produced by acute bilateral cervical vagotomy. The results indicate that 1) with the cardiopulmonary receptors alone operative, the arterial blood pressure response to exercise is abnormal, 2) cardiopulmonary receptors do not contribute to the moment-to-moment modulation of arterial pressure, and 3) the carotid sinuses, aortic arch, and cardiopulmonary receptors are all involved in determining the mean level of arterial blood pressure. It is concluded that vagally innervated cardiopulmonary receptors do not have a significant role in regulating arterial blood pressure during exercise but are involved in establishing the general level of arterial blood pressure.
在清醒犬处于对照状态以及压力感受性反射逐渐被阻断后，监测其静息时以及进行两种不同严重程度运动期间的平均动脉血压、心率和心输出量。采用主动脉弓去神经支配以及血管分离并对颈动脉窦加压的方法来阻断动脉压力感受性反射。随后通过急性双侧颈迷走神经切断术来阻断心肺传入神经。结果表明：1）仅心肺感受器起作用时，运动时的动脉血压反应异常；2）心肺感受器对动脉血压的瞬间调节无作用；3）颈动脉窦、主动脉弓和心肺感受器均参与确定动脉血压的平均水平。得出的结论是，由迷走神经支配的心肺感受器在运动期间调节动脉血压方面无显著作用，但参与确立动脉血压的总体水平。
