May C R
Ann Emerg Med. 1983 Mar;12(3):171-3. doi: 10.1016/s0196-0644(83)80562-9.
Reported is a case of baclofen overdose in a 23-year-old woman. The patient manifested typical symptoms of baclofen overdose, including hypotonia, respiratory depression, and seizures. She was treated successfully with positive pressure ventilation, sedation, and intravenous antibiotics, and was discharged from the hospital on the 14th day following admission with no residual neurological signs, to be followed up in medical and psychiatric outpatient clinics. As baclofen becomes increasingly popular in the treatment of muscle spasm in certain neurological disorders, its availability for misuse increases.
报告了一例23岁女性巴氯芬过量的病例。该患者表现出巴氯芬过量的典型症状,包括肌张力减退、呼吸抑制和癫痫发作。她通过正压通气、镇静和静脉注射抗生素成功治愈,并在入院后第14天出院,无残留神经体征,随后在医学和精神科门诊进行随访。随着巴氯芬在某些神经系统疾病的肌肉痉挛治疗中越来越受欢迎,其被滥用的可能性也在增加。