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巴氯芬过量致心脏传导异常:病例报告及文献综述

Baclofen overdose with cardiac conduction abnormalities: case report and review of the literature.

作者信息

Nugent S, Katz M D, Little T E

出版信息

J Toxicol Clin Toxicol. 1986;24(4):321-8. doi: 10.3109/15563658608992596.

DOI:10.3109/15563658608992596
PMID:3018274
Abstract

Cardiac conduction abnormalities and hypertension developed in a patient who ingested approximately 500 mg of baclofen (Lioresal). The patient also exhibited the more common features of baclofen overdose including coma, respiratory depression, hypotonia, and hyporeflexia. A review of the literature and a discussion of the interesting manifestations and treatment of baclofen overdose are included.

摘要

一名摄入约500毫克巴氯芬(力奥来素)的患者出现了心脏传导异常和高血压。该患者还表现出巴氯芬过量更常见的特征,包括昏迷、呼吸抑制、肌张力减退和反射减退。本文还包括对文献的回顾以及对巴氯芬过量有趣表现和治疗方法的讨论。

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