Liebman H A, McGehee W G, Patch M J, Feinstein D I
Ann Intern Med. 1983 Mar;98(3):330-3. doi: 10.7326/0003-4819-98-3-330.
Serial coagulation studies were done in four women with acute fatty liver of pregnancy. All had coagulopathy, laboratory evidence of diffuse intravascular coagulation, and marked depletion of plasma antithrombin III. Two of these women had persistent intravascular coagulation for 4 days after delivery. The others had prompt control of intravascular coagulation coincident with elevation of the antithrombin III concentration by plasma transfusion. Severe antithrombin III depression may be a major cause of the persistent intravascular clotting and can be corrected by plasma transfusion.
对四名患有妊娠急性脂肪肝的女性进行了连续凝血研究。所有患者均有凝血功能障碍、弥散性血管内凝血的实验室证据以及血浆抗凝血酶III显著减少。其中两名女性在分娩后持续血管内凝血4天。其他患者通过输血使抗凝血酶III浓度升高，同时血管内凝血得到迅速控制。严重的抗凝血酶III降低可能是持续性血管内凝血的主要原因，可通过输血纠正。
