Dobrokhotov V N, Bystrenina N G, Podderiugina G I
Biull Eksp Biol Med. 1983 Apr;95(4):84-5.
A significant decrease in the rate of cell entering into mitosis was discovered in exocrine cells of the pancreas and in liver parenchymal cells of 7-day-old rats after colchamine injections at varying times of day. These data indicate that the colchamine method should not be applied to the assessment of mitosis duration and cell proliferation rates in animal tissues.
在一天中的不同时间注射秋水仙胺后，发现7日龄大鼠胰腺外分泌细胞和肝实质细胞进入有丝分裂的细胞比率显著下降。这些数据表明，秋水仙胺法不适用于评估动物组织中有丝分裂持续时间和细胞增殖速率。
