Funch D P, Marshall J
J Psychosom Res. 1983;27(1):77-83. doi: 10.1016/0022-3999(83)90112-5.
This study focused on the relationship of objective and subjective stresses to survival from breast cancer. The potential mediating roles of social support and age were also considered. This prospective study involved 208 white female breast cancer patients diagnosed between 1958 and 1960. At the time of diagnosis, subjects were interviewed regarding objective and subjective stress and social support present in the 5-year period preceding their diagnosis. Twenty years later, survival was calculated. The relationships between stress and survival were examined for three age groups: 15-45, 46-60, and 61 and older. Objective stress was related to survival for the oldest group while subjective stress was related to survival for the youngest group. Neither stress was related to survival for women aged 46-60. Social involvement was independently related to survival although it was not a mediator in the stress-survival relationship. Using the entire sample, stage of cancer at diagnosis was the best predictor of survival. However, when women aged 46-60 were eliminated from the analysis, stress and social involvement accounted for twice as much variance in survival as stage.
本研究聚焦于客观压力与主观压力和乳腺癌患者生存之间的关系。同时也考虑了社会支持和年龄的潜在中介作用。这项前瞻性研究纳入了208名在1958年至1960年间被诊断为乳腺癌的白人女性患者。在诊断时,对受试者进行了访谈,询问其在诊断前5年期间存在的客观压力、主观压力和社会支持情况。20年后,计算生存率。对三个年龄组(15 - 45岁、46 - 60岁以及61岁及以上)的压力与生存之间的关系进行了研究。客观压力与最年长组的生存相关,而主观压力与最年轻组的生存相关。对于46 - 60岁的女性,两种压力均与生存无关。社会参与与生存独立相关,尽管它在压力 - 生存关系中并非中介因素。在使用整个样本时,诊断时的癌症分期是生存的最佳预测因素。然而,当将46 - 60岁的女性从分析中排除后,压力和社会参与对生存差异的解释是分期的两倍。