风疹免疫力：血凝抑制法与放射免疫分析法抗体检测方法的比较
Rubella immunity: comparison of hemagglutination inhibition and radioimmunoassay antibody methods.
作者信息
Harris R E, Smith K O, Gehle W D, Dupuy H J
出版信息
Obstet Gynecol. 1980 May;55(5):603-7.
A threshold (1:10) rubella antibody hemagglutination inhibition (HAI) titer was obtained for 288 of 6537 (4.4%) obstetric patients. Random sera from 84 of these patients were compared for rubella antibody by both HAI and a very sensitive radioimmunoassay (RIA) technique. By RIA, 17% of the sera had no detectable rubella antibody, suggesting that those patients were truly susceptible to rubella. In addition, 8 of 55 paired prevaccine and postvaccine sera with titer increases demonstrated by HAI were analyzed by RIA. Seven of the 8 prevaccine sera were shown to have no rubella virus antibody by RIA, and RIA showed seroconversion in all 8 postvaccine sera.
在6537名产科患者中，有288名（4.4%）的风疹抗体血凝抑制（HAI）效价达到了临界值（1:10）。通过HAI和一种非常灵敏的放射免疫测定（RIA）技术，对其中84名患者的随机血清进行了风疹抗体比较。采用RIA检测时，17%的血清未检测到风疹抗体，这表明这些患者确实对风疹易感。此外，对55对经HAI检测显示效价升高的疫苗接种前和接种后血清中的8对进行了RIA分析。8份疫苗接种前血清中的7份经RIA检测显示没有风疹病毒抗体，而RIA显示所有8份疫苗接种后血清都发生了血清转化。
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