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过敏性眼病中的结膜嗜酸性粒细胞。

Conjunctival eosinophils in allergic ocular disease.

作者信息

Abelson M B, Madiwale N, Weston J H

出版信息

Arch Ophthalmol. 1983 Apr;101(4):555-6. doi: 10.1001/archopht.1983.01040010555002.

DOI:10.1001/archopht.1983.01040010555002
PMID:6838412
Abstract

Tarsal conjunctival scrapings of 317 patients with allergic ocular disease demonstrated that eosinophils were found infrequently in scrapings of patients with mild allergic conditions and were found in only 63% (17/27) of the patients with vernal conjunctivitis. In similar studies of a 12-year-old boy with vernal keratoconjunctivitis, no eosinophils were recovered in his scraping, even though 12 eosinophils were found in five high-power fields of his biopsy specimen. We conclude that eosinophils present in the deep and superficial conjunctival tissues may not be recovered in scrapings; their absence from scrapings should not preclude the diagnosis of allergic ocular disease.

摘要

对317例过敏性眼病患者的睑结膜刮片检查显示,轻度过敏患者的刮片中很少发现嗜酸性粒细胞,春季结膜炎患者中只有63%(17/27)的患者刮片中发现嗜酸性粒细胞。在一项针对一名12岁春季角结膜炎男孩的类似研究中,尽管在其活检标本的五个高倍视野中发现了12个嗜酸性粒细胞,但在他的刮片中未发现嗜酸性粒细胞。我们得出结论,结膜深层和浅层组织中存在的嗜酸性粒细胞可能无法在刮片中检测到;刮片中未发现嗜酸性粒细胞不应排除过敏性眼病的诊断。

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1
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引用本文的文献

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Immun Inflamm Dis. 2020 Mar;8(1):3-7. doi: 10.1002/iid3.278. Epub 2019 Dec 5.
2
Dietary ω-3 fatty acids alter the lipid mediator profile and alleviate allergic conjunctivitis without modulating T2 immune responses.膳食 ω-3 脂肪酸可改变脂质介质谱并缓解变应性结膜炎,而不调节 T2 免疫反应。
FASEB J. 2019 Mar;33(3):3392-3403. doi: 10.1096/fj.201801805R. Epub 2018 Nov 1.
3
Conjunctival allergen challenge: models in the investigation of ocular allergy.
结膜变应原激发试验:眼部过敏研究中的模型
Curr Allergy Asthma Rep. 2003 Jul;3(4):363-8. doi: 10.1007/s11882-003-0100-z.
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Epithelial cells in ocular allergy.眼部过敏中的上皮细胞。
Curr Allergy Asthma Rep. 2003 Jul;3(4):352-7. doi: 10.1007/s11882-003-0098-2.
5
Allergic eye disease mechanisms.过敏性眼病机制。
Br J Ophthalmol. 1998 Oct;82(10):1203-14. doi: 10.1136/bjo.82.10.1203.
6
Eosinophil cationic protein in tears in allergic conjunctivitis.过敏性结膜炎患者泪液中的嗜酸性粒细胞阳离子蛋白
Br J Ophthalmol. 1996 Jun;80(6):556-60. doi: 10.1136/bjo.80.6.556.
7
Immunology of the eye--1983.眼部免疫学——1983年
Surv Immunol Res. 1984;3(2-3):217-20. doi: 10.1007/BF02918798.
8
Cytological and immunohistochemical study of the limbal form of vernal keratoconjunctivitis by the replica technique.通过复型技术对春季角结膜炎睑裂部型进行细胞学和免疫组织化学研究。
Br J Ophthalmol. 1987 Nov;71(11):867-72. doi: 10.1136/bjo.71.11.867.