Olving J H, Olaisen B, Teisberg P, Gedde-Dahl T, Thorsby E
Hum Genet. 1977 Jun 30;37(2):125-9. doi: 10.1007/BF00393574.
C6 typing was performed in a family material by two different techniques: serum or plasma samples were subjected either to high-voltage agarose gel electrophoresis or to isoelectric focusing in polyacrylamide gel slabs. Proteins with C6 activity were then visualized by a specific, hemolytic assay. In 81 unrelated adults within the family material the following allele frequencies were found: C6A:0.61 and C6B:0.39. Linkage studies exclude linkage between C6 and HLA region marker loci, and also between C6 and another chromosome 6 marker locus PGM3.
采用两种不同技术对一个家系材料进行C6分型：血清或血浆样本分别进行高压琼脂糖凝胶电泳或聚丙烯酰胺凝胶板等电聚焦。然后通过特定的溶血试验使具有C6活性的蛋白质可视化。在家系材料中的81名无关成年人中发现了以下等位基因频率：C6A：0.61和C6B：0.39。连锁研究排除了C6与HLA区域标记位点之间以及C6与另一个6号染色体标记位点PGM3之间的连锁关系。
