通过组织培养证实的家族性高胆固醇血症中跟腱厚度的干板X线照相测定。

Xeroradiographic determination of Achilles tendon thickness in familial hypercholesterolemia confirmed by tissue cultures.

作者信息

Seidl O, Keller C, Berger H, Wolfram G, Zöllner N

出版信息

Atherosclerosis. 1983 Feb;46(2):163-72. doi: 10.1016/0021-9150(83)90107-7.

Abstract

Twenty-three patients with familial hypercholesterolemia (FHC) confirmed by tissue cultures of skin fibroblasts (2 homozygotes, 21 heterozygotes) and 3 patients with sporadic hypercholesterolemia were evaluated for Achilles tendon (AT) thickness by xeroradiography. Both homozygotes had thick ATs and coronary heart disease (CHD), 20 heterozygotes had thick ATs, but only 8 of them had CHD. One heterozygote had a small AT value, but CHD for a long time. The 3 patients with sporadic hypercholesterolemia, one with CHD, had small AT. There was no correlation between serum cholesterol concentration and AT thickness, between age and AT thickness, nor between AT thickness and CHD.

摘要

通过皮肤成纤维细胞组织培养确诊的23例家族性高胆固醇血症（FHC）患者（2例纯合子，21例杂合子）和3例散发性高胆固醇血症患者接受了干板X线照相术评估跟腱（AT）厚度。2例纯合子均有增厚的跟腱和冠心病（CHD），20例杂合子有增厚的跟腱，但其中只有8例患有冠心病。1例杂合子跟腱值较小，但患有冠心病已久。3例散发性高胆固醇血症患者中，1例患有冠心病，其跟腱较小。血清胆固醇浓度与跟腱厚度之间、年龄与跟腱厚度之间以及跟腱厚度与冠心病之间均无相关性。