McConville B J, Soudek D, Sroka H, Coté J, Boag L, Berry J
Can J Psychiatry. 1983 Feb;28(1):8-13. doi: 10.1177/070674378302800103.
In a study of 41 inpatient boys with psychiatric disorders, it was found that this group had significantly increased length of the long arm of the Y chromosome (Yq+) as compared to a normal control group. The length of the Y chromosome in the inpatient group correlated with psychiatric symptom severity, hyperactivity, parental psychopathology and paternal alcoholism. A further study of minor chromosomal variants in 56 inpatient boys and girls revealed no differences in individual or pooled variants in the patient group, as compared to the control group. However, those in the patient group with one or more variants showed more severe psychiatric and other psychosocial symptoms than those in the group without variants. Those who had both longer Y chromosomes and a minor chromosomal variant had more severe psychiatric symptom severity.
在一项针对41名患有精神疾病的住院男孩的研究中，发现该组与正常对照组相比，Y染色体长臂长度显著增加（Yq+）。住院组的Y染色体长度与精神症状严重程度、多动、父母精神病理学和父亲酗酒相关。对56名住院男孩和女孩的微小染色体变异进行的进一步研究表明，与对照组相比，患者组在个体或合并变异方面没有差异。然而，患者组中具有一个或多个变异的人比没有变异的组表现出更严重的精神和其他心理社会症状。那些Y染色体较长且有微小染色体变异的人精神症状严重程度更高。
