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[抗肿瘤免疫的形态学关联。II. 肿瘤基质的反应]

[Morphologic correlations of anti-tumor immunity. II. Reactions of the tumor stroma].

作者信息

Jansa P, Pastrnák A

出版信息

Cesk Patol. 1983 Feb;19(1):27-30.

PMID:6839382
Abstract

In three groups of oncological patients (with oral, stomach, and breast cancer), standard testing of the tumour stromal reaction was made in relation to life expectancy. The quantification of stromal reaction, cell infiltration topography and representation as well as necroses of tumour tissue were analysed. A direct correlation between the stromal reaction intensity and the life expectancy could be shown for the stomach cancer only for the time being. A close contact of the stromal and tumour cells in this cancer could be also interpreted as a favourable prognostic sign. When using this simple testing for oral and breast cancer there were some not quite positive hints of correlation.

摘要

在三组肿瘤患者(口腔癌、胃癌和乳腺癌患者)中,针对预期寿命进行了肿瘤基质反应的标准检测。分析了基质反应的量化、细胞浸润的拓扑结构和表现以及肿瘤组织的坏死情况。目前仅在胃癌中显示出基质反应强度与预期寿命之间存在直接相关性。这种癌症中基质细胞与肿瘤细胞的紧密接触也可被解释为一种有利的预后迹象。在对口腔癌和乳腺癌进行这种简单检测时,存在一些不太明显的相关性提示。

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