[甲状腺素和甲状腺切除术对豚鼠组织中腺苷酸脱氨酶活性的影响]
[Effect of thyroxine and thyroidectomy on the activity of adenylate deaminase in the tissues of guinea pigs].
作者信息
Kryshkova A M, Angelov A M, Mikhaĭlova M B
出版信息
Probl Endokrinol (Mosk). 1978 Jul-Aug;24(4):69-71.
The authors studied the influence of thyroxin and thyroidectomy on adenylate deaminase activity in the liver, the myocardium, the brain and the skeletal muscles of guinea pigs. Thyroxin used in normal animals (200 microgram/100 g of body weight for 7 days) failed to alter the enzymatic activity in the tissues under study, whereas in thyroidectomized guinea pigs (50 microgram/100 g of body weight at the same interval)--it enhanced this activity. Thyroidectomy diminished the adenylate deaminase activity in the skeletal muscles and considerably increased it in the myocardium and in the brain.
作者研究了甲状腺素和甲状腺切除对豚鼠肝脏、心肌、脑和骨骼肌中腺苷酸脱氨酶活性的影响。正常动物使用甲状腺素（200微克/100克体重，持续7天）未能改变所研究组织中的酶活性，而在甲状腺切除的豚鼠中（相同间隔，50微克/100克体重）——它增强了这种活性。甲状腺切除降低了骨骼肌中的腺苷酸脱氨酶活性，并显著增加了心肌和脑中的该活性。
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